Team
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EDUCATION AND TRAINING
DPhil in Infection, Immunology and Translational Medicine, University of Oxford BSc in Biology, Imperial College London
BIOGRAPHY
Benjamin Nilsson-Payant is a postdoctoral fellow in the tenOever lab working on the biology of the influenza A virus RNA-dependent RNA polymerase (RdRp). His research focuses on elucidating the mechanisms of viral RNA genome replication and how the viral nuclear export protein (NEP) and small viral RNA (svRNA) produced by the virus contribute to RdRp function.
Previous to his work in the tenOever lab, Benjamin completed his bachelor degree in Biology at Imperial College London before joining Ervin Fodor’s lab at the University of Oxford for his Ph.D. studies. For his thesis, he studied the virus-host interactions determining host specificity of the influenza A virus RdRp.
PUBLICATIONS
The NF-κB transcriptional footprint is essential for SARS-CoV-2 replication
Nilsson-Payant BE, Uhl S, Grimont A, Doane AS, Cohen P, Patel RS, Higgins CA, Acklin JA, Bram Y, Chandar V, Blanco-Melo D, Panis M, Lim JK, Elemento O, Schwartz RE, Rosenberg BR, Chandwani R, tenOever BR
J Virol. 2021 Sep 15:JVI0125721 15/09/2021
PMID: 34523966
A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics.
Longlong Si # 1, Haiqing Bai # 1, Melissa Rodas 1, Wuji Cao 1, Crystal Yuri Oh 1, Amanda Jiang 1 2, Rasmus Moller 3, Daisy Hoagland 3, Kohei Oishi 3, Shu Horiuchi 3, Skyler Uhl 3, Daniel Blanco-Melo 3, Randy A Albrecht 3, Wen-Chun Liu 3, Tristan Jordan 3, Benjamin E Nilsson-Payant 3, Ilona Golynker 3, Justin Frere 3, James Logue 4, Robert Haupt 4, Marisa McGrath 4, Stuart Weston 4, Tian Zhang 5, Roberto Plebani 1 6, Mercy Soong 1, Atiq Nurani 1, Seong Min Kim 1, Danni Y Zhu 1, Kambez H Benam 1 7 8, Girija Goyal 1, Sarah E Gilpin 1, Rachelle Prantil-Baun 1, Steven P Gygi 5, Rani K Powers 1, Kenneth E Carlso n 1, Matthew Frieman 4, Benjamin R tenOever 3, Donald E Ingber 9 10.
Nature Biomedical Engineering 03/05/2021
PMID: 33941899
Reduced Nucleoprotein Availability Impairs Negative-Sense RNA Virus Replication and Promotes Host Recognition.
Nilsson-Payant BE, Blanco-Melo D, Uhl S, Escudero-Pérez B, Olschewski S, Thibault P, Panis M, Rosenthal M, Muñoz-Fontela C, Lee B, tenOever BR.
J Virol 12/04/2021
PMID: 33568513
Identification of SARS-CoV-2 Inhibitors using Lung and Colonic Organoids
Han Y, Duan X, Yang L, Nilsson-Payant BE, Wang P, Duan F, Tang X, Yaron TM, Zhang T, Uhl S, Bram Y, Richardson C, Zhu J, Zhao Z, Redmond D, Houghton S, Nguyen DT, Xu D, Wang X, Jessurun J, Borczuk A, Huang Y, Johnson JL, Liu Y, Xiang J, Wang H, Cantley LC, tenOever BR, Ho DD, Pan FC, Evans T, Chen HJ, Schwartz RE, Chen S.
Nature 28/01/2021
PMID: 33116299
