Team

Benjamin Nilsson-Payant

Postdoctoral fellow, 2018 – 2021
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EDUCATION AND TRAINING

DPhil in Infection, Immunology and Translational Medicine, University of Oxford BSc in Biology, Imperial College London

BIOGRAPHY

Benjamin Nilsson-Payant is a postdoctoral fellow in the tenOever lab working on the biology of the influenza A virus RNA-dependent RNA polymerase (RdRp). His research focuses on elucidating the mechanisms of viral RNA genome replication and how the viral nuclear export protein (NEP) and small viral RNA (svRNA) produced by the virus contribute to RdRp function.

Previous to his work in the tenOever lab, Benjamin completed his bachelor degree in Biology at Imperial College London before joining Ervin Fodor’s lab at the University of Oxford for his Ph.D. studies. For his thesis, he studied the virus-host interactions determining host specificity of the influenza A virus RdRp.

PUBLICATIONS

Dual-Reporter System for Real-Time Monitoring of SARS-CoV-2 Main Protease Activity in Live Cells Enables Identification of an Allosteric Inhibition Path

Bram Y, Duan X, Nilsson-Payant BE, Chandar V, Wu H, Shore D, Fajardo A, Sinha S, Hassan N, Weinstein H, TenOever BR, Chen S, Schwartz RE

10.1021/acsbiomedchemau.2c00034 21/12/2022

PMID: 36570071

Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication.

Yaron TM, Heaton BE, Levy TM, Johnson JL, Jordan TX, Cohen BM, Kerelsky A, Lin TY, Liberatore KM, Bulaon DK, Van Nest SJ, Koundouros N, Kastenhuber ER, Mercadante MN, Shobana-Ganesh K, He L, Schwartz RE, Chen S, Weinstein H, Elemento O, Piskounova E, Nilsson-Payant BE, Lee G, Trimarco JD, Burke KN, Hamele CE, Chaparian RR, Harding AT, Tata A, Zhu X, Tata PR, Smith CM, Possemato AP, Tkachev SL, Hornbeck PV, Beausoleil SA, Anand SK, Aguet F, Getz G, Davidson AD, Heesom K, Kavanagh-Williamson M, Matthews DA, tenOever BR, Cantley LC, Blenis J, Heaton NS

Science Signaling, 15(757):eabm08. 25/10/2022

PMID: 36282911

A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants

Han Y, Tan L, Zhou T, Yang L, Carrau L, Lacko LA, Saeed M, Zhu J, Zhao Z, Nilsson-Payant BE, Lira Neto FT, Cahir C, Giani AM, Chai JC, Li Y, Dong X, Moroziewicz D; NYSCF Global Stem Cell Array Team; Paull D, Zhang T, Koo S, Tan C, Danziger R, Ba Q, Feng L, Chen Z, Zhong A, Wise GJ, Xiang JZ, Wang H, Schwartz RE, tenOever BR, Noggle SA, Rice CM, Qi Q, Evans T, Chen S.

10.1016/j.stem.2022.09.008 06/10/2022

PMID: 36206731

Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19

Paôline Laurent, Chao Yang, André F Rendeiro, Benjamin E Nilsson-Payant, Lucia Carrau, Vasuretha Chandar, Yaron Bram, Benjamin R tenOever, Olivier Elemento, Lionel B Ivashkiv, Robert E Schwartz, Franck J Barrat

10.1126/sciimmunol.add4906 09/09/2022

PMID: 36083891