Team
EDUCATION AND TRAINING
B.A. Music from University of California, Berkeley 2018 Current MD/PhD student at NYU
BIOGRAPHY
Sydney is an MD/PhD student in the tenOever lab. Sydney grew up in Bethesda, MD and graduated from the University of California, Berkeley with a degree in Trombone Performance. Between undergraduate and graduate school she worked as a Research Specialist in the lab of Dr. Kathleen Collins where she investigated the biochemical properties of a non-LTR reverse transcriptase. As she begins her work in the tenOever lab, Sydney is interested in furthering our understanding of viral pathogenesis and utilizing viral vectors for genetic manipulation.
PUBLICATIONS
Streamlined and sensitive mono- and di-ribosome profiling in yeast and human cells
Ferguson L, Upton HE, Pimentel SC, Mok A, Lareau LF, Collins K, Ingolia NT.
Nat Methods. 2023 Nov;20(11):1704-1715. 20/11/2023
PMID: 37783882
Nanopore molecular trajectories of a eukaryotic reverse transcriptase reveal a long-range RNA structure sensing mechanism
Shaw A, Craig JM, Amiri H, Kim J, Upton HE, Pimentel SC, Huang JR, Marqusee S, Collins K, Gundlach JH, Bustamante CJ.
bioRxiv [Preprint]. 2023 Nov 1:2023.04.05.535757. 05/04/2023
PMID: 37066208
Separable structural requirements for cDNA synthesis, nontemplated extension, and template jumping by a non-LTR retroelement reverse transcriptase
Pimentel SC, Upton HE, Collins K.
J Biol Chem. 2022 Mar;298(3):101624. 21/01/2022
PMID: 35065960
Low-bias ncRNA libraries using ordered two-template relay: Serial template jumping by a modified retroelement reverse transcriptase
Upton HE, Ferguson L, Temoche-Diaz MM, Liu XM, Pimentel SC, Ingolia NT, Schekman R, Collins K.
Proc Natl Acad Sci U S A. 2021 Oct 19;118(42):e2107900118. 19/10/2021
PMID: 34649994